FIGURE 2.1.
Plots of ST-segment depression against HR during both the exercise
and first three minutes of postexercise recovery (i.e., ST/HR diagrams)
illustrating the computerized determination of the ST/HR hysteresis from
a single lead.
In these diagrams, ST depression is plotted in an upward
direction on the vertical axis, and the negative values represent ST elevation.
Typical ST/HR diagrams are shown for a clinically normal subject (upper
left panel) with an unambiguously negative hysteresis in ST depression
against HR (i.e., clockwise hysteresis loop in recovery) and for a patient
with coronary artery disease (upper right panel) with an unambiguously
positive hysteresis in ST depression against HR (i.e., counterclockwise
hysteresis loop in recovery). In the lower panels, more complex ST/HR diagrams
are shown for a normal patient (lower left panel) and for a patient with
coronary artery disease (lower right panel), in which cases the direction
of the hysteresis in ST depression against HR was changed during the postexercise
recovery phase. In graphical sense, the ST/HR hysteresis was obtained by
subtracting the area of negative hysteresis from the area of positive hysteresis
and dividing the resulted net area by the HRrec. HRexe = maximum HR; HRrec
= the minimum heart rate of recovery; HRrec = HRexe-HRrec; 3v-CAD = three-vessel
coronary artery disease.